- Review Article
- Infection
- Pathogenetic and etiologic considerations of febrile seizures
-
Ji Yoon Han, Seung Beom Han
-
Clin Exp Pediatr. 2023;66(2):46-53. Published online January 13, 2023
-
|
· Inflammatory responses accompanying fever increase neuronal excitability in the central nervous system, which in turn provokes seizures.
· Fever in children with febrile seizures is usually caused by common respiratory viruses, the distributions of which match those of seasonal community-acquired respiratory tract infections.
· Several genetic variations in ion channels seem associated with neuronal hyperexcitability in children with febrile seizures. |
-
-
- Neurology
- Genetic tests by next-generation sequencing in children with developmental delay and/or intellectual disability
-
Ji Yoon Han, In Goo Lee
-
Clin Exp Pediatr. 2020;63(6):195-202. Published online November 4, 2019
-
|
Developments in next-generation sequencing (NGS) techogies have assisted in clarifying the diagnosis and treatment of developmental delay/intellectual disability (DD/ID) via molecular genetic testing. Advances in DNA sequencing technology have not only allowed the evolution of targeted panels but also, and more currently enabled genome-wide analyses to progress from research era to clinical practice. Broad acceptance of accuracy- guided targeted gene... |
-
-
- Original Article
- Outcome of allogeneic hematopoietic stem cell transplantation for childhood acute lymphoblastic leukemia in second complete remission: a single institution study
-
Eun-Jung Lee, Ji Yoon Han, Jae Wook Lee, Pil-Sang Jang, Nack-Gyun Chung, Dae-Chul Jeong, Bin Cho, Hack-Ki Kim
-
Clin Exp Pediatr. 2012;55(3):100-106. Published online March 16, 2012
-
|
Purpose The survival rate for childhood acute lymphoblastic leukemia (ALL) has improved significantly. However, overall prognosis for the 20 to 25% of patients who relapse is poor, and allogeneic hematopoietic stem cell transplantation (HSCT) offers the best chance for cure. In this study, we identified significant prognostic variables by analyzing the outcomes of allogeneic HSCT in ALL patients in second complete... |
-
-
|